What is semaglutide?

Semaglutide is a medication that belongs to a class of drugs called glucagon-like peptide-1 (GLP-1) receptor agonists. It works by mimicking the effects of a hormone called GLP-1, which is naturally produced in the body. GLP-1 is released by the gut in response to food intake and helps to regulate blood sugar levels by stimulating insulin secretion and reducing glucagon production.

Semaglutide is used to treat type 2 diabetes and has been shown to improve glycemic control, reduce the risk of cardiovascular events, and promote weight loss. It is available in a variety of formulations, including a subcutaneous injection that can be administered once a week.

In addition to its use in diabetes, semaglutide has also been approved by the FDA for the treatment of obesity in adults with a BMI of 30 or greater or those with a BMI of 27 or greater and at least one weight-related condition, such as hypertension or type 2 diabetes. The drug is typically used in combination with a reduced-calorie diet and increased physical activity to help promote weight loss.

How does semaglutide work?

1. Reduces appetite: Semaglutide works by mimicking the effects of a hormone called glucagon-like peptide-1 (GLP-1) in the body. GLP-1 is known to suppress appetite and reduce food intake. By activating GLP-1 receptors in the brain, semaglutide can help to reduce hunger and make it easier to stick to a calorie-controlled diet.
2. Increases satiety: Semaglutide can also increase feelings of fullness or satiety, making it easier to avoid overeating. This effect is thought to be due to the drug’s ability to slow down the emptying of the stomach and increase the production of certain hormones that regulate appetite.
3. Improves metabolic function: Semaglutide can improve metabolic function, which may contribute to weight loss. The drug can help to regulate blood sugar levels and increase insulin sensitivity, both of which can lead to more efficient fat burning.
4. Increases physical activity: Some studies have suggested that semaglutide may also increase physical activity levels, which can aid in weight loss. This effect may be due to the drug’s ability to improve energy levels and reduce fatigue.

It is important to note that semaglutide is not a magic pill for weight loss and should only be used under the guidance of a healthcare professional. A healthy diet and regular exercise are still essential for long-term weight loss success.  If you are in the Kansas City area, reach out to schedule a consultation and see if semaglutide is right for you.